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目的:研究对尿毒症皮肤瘙痒采取血液灌流与血液透性周围神经病变的临床疗效。方法:选取我院收治的61例尿毒症皮肤瘙痒患者作为此次研究的分析对象,并按随机分配数字表达法将其分为研究组与对照组。其中,对照组的总例数为30例,给予该组患者血液透析进行治疗;研究组的总例数为31例,给予该组患者血液灌流联合血液透析进行治疗,观察并比较两组患者的临床效果与临床相关指标。结果:对照组的总有效率比研究组低,研究组的甲状旁腺激素、血β2微球蛋白、血肌酐及血磷优于对照组,有统计学差异存在(P<0.05)。结论:将血液灌流与血液透性周围神经病变应用于尿毒症皮肤瘙痒的治疗中,能取得确切的效果,建议临床应用与推广。
Objective: To study the clinical efficacy of hemoperfusion and hemodialysis peripheral neuropathy on pruritus of uremic skin. Methods: Totally 61 patients with pruritus of uremic skin treated in our hospital were selected as the analysis objects and divided into study group and control group according to random distribution of digital expression method. Among them, the control group of 30 cases, giving the group hemodialysis treatment; the study group a total of 31 cases, giving the group hemoperfusion combined with hemodialysis for treatment, observation and comparison of two groups of patients Clinical effect and clinical related indicators. Results: The total effective rate of the control group was lower than that of the study group. The parathyroid hormone, β2 microglobulin, serum creatinine and phosphorus in the study group were better than those in the control group (P <0.05). Conclusion: The application of hemoperfusion and hemodialysis peripheral neuropathy in the treatment of pruritus of uremic skin can achieve the exact effect, and the clinical application and promotion are suggested.