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目的 探讨矽肺经全肺灌洗前后心血管形态与功能变化 ,以判断其疗效。方法 对 3 0例Ⅰ、Ⅱ期矽肺患者全肺灌洗前后的胸部X线片测量心胸比率 ,右下肺动脉降支与气管横径比值 ,并应用多普勒超声心动图进行左室收缩功能及肺动脉血流参数测定 ,以 3 0名健康者作为对照组 ,采用t检验进行统计学处理。结果 全肺灌洗后矽肺患者的心胸比率。右肺动脉降支与气管横径比值缩小 (Ρ <0 .0 1) ,超声心动图的左室收缩功能参数提高 ,肺动脉血流参数下降 (Ρ <0 .0 1) ,并接近健康对照水平 (Ρ >0 .0 5 )。结论 矽肺经全肺灌洗治疗后心功能有明显改善 ,心血管X线及多普勒超声心动图检查在全肺灌洗治疗矽肺的疗效评价中具有重要的作用。
Objective To investigate the changes of cardiovascular morphology and function before and after the whole lung lavage in silicosis in order to evaluate its curative effect. Methods Thoracic radiography was performed on 30 patients with stage I and II silicosis before and after thoracic lavage. Cardiothoracic ratio, right descending pulmonary artery descending branch and tracheal diameter ratio were measured. Doppler echocardiography was used to measure left ventricular systolic function and Pulmonary artery blood flow parameters were measured, and 30 healthy controls were used as the control group. The t-test was used for statistical analysis. Results Cardiothoracic ratio in patients with silicosis after total lung lavage. The ratio of descending branch of the right pulmonary artery to tracheal diameter was reduced (P <0.01), echocardiographic parameters of left ventricular systolic function were increased, pulmonary artery flow parameters were decreased (P <0.01), and close to the healthy control level Ρ> 0 .0 5). Conclusion The heart function of silicosis after pulmonary perfusion has been significantly improved. The evaluation of cardiovascular X-ray and Doppler echocardiography in the evaluation of the therapeutic effect of whole lung lavage on silicosis plays an important role.