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2013年10月~2014年10月300例我院住院腹部手术的患者,按随机数字表随机分为观察组和对照组各150例。对照组采用术后常规使用抗生素,观察组采用预防性抗生素指导干预,比较两组病人术后感染、术后并发症、平均住院天数、总药物费用。观察组术后切口感染率、术后并发症、平均住院天数、总药物费用均较对照组明显减少,差异有显著性差异(P<0.05)。腹部围手术期预防性应用抗生素能预防感染、降低术后并发症、为病人减少住院天数及医疗费用,达到“安全、有效、经济”的目的,值得临床推广运用。
From October 2013 to October 2014, 300 cases of hospitalized abdominal surgery in our hospital were randomly divided into observation group and control group according to random number table. The patients in the control group were treated with antibiotics routinely. The patients in the observation group were guided by prophylactic antibiotics. Postoperative infection, postoperative complications, average days of hospitalization and total drug cost were compared between the two groups. Incision infection rate, postoperative complications, average days of hospitalization and total drug cost in the observation group were significantly decreased compared with the control group, the difference was significant (P <0.05). Perioperative prophylactic application of antibiotics in the abdomen can prevent infection and reduce postoperative complications, reduce the number of days of hospitalization and medical expenses for patients and achieve the goal of “safe, effective and economical”, which is worthy of clinical promotion and application.