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阴茎硬结症的治疗一直是困扰患者和泌尿男科医师的难题。目前口服药物多数被认为无效,剩下的方法需要严格掌握适应症,有的尚存争议。而最终的手术治疗则可能伴发阴茎缩短或勃起功能障碍等并发症。溶组织羧菌胶原酶被证实能够有效溶解阴茎海绵体斑块的作用,被美国食品药品管理局批准成为第一个用于治疗阴茎硬结症的药物。本文旨在介绍这种新的阴茎硬结症治疗方式的特点、安全性、有效性及治疗方法。以期让更多的泌尿男科大夫和患者受益。
The treatment of penile sclerosis has been a dilemma for patients and urological gynecologists. At present, the majority of oral drugs are considered invalid, the remaining methods need to strictly control indications, and some are still controversial. The final surgical treatment may be accompanied by penile shortening or erectile dysfunction and other complications. Rosiglitazone has been shown to be effective at dissolving plaque in the penis and was approved by the U.S. Food and Drug Administration as the first drug to treat penile sclerosis. This article aims to introduce the characteristics, safety, efficacy and treatment of this new treatment for penile sclerosis. With a view to make more urology male doctor and patient benefit.