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目的观察不同的通气模式对COPD合并Ⅱ型呼吸衰竭患者的影响。方法选取合并Ⅱ型呼吸衰竭的慢性阻塞性肺疾病(COPD)患者80例,随机分为研究组和对照组各40例:对照组采用同步间歇指令通气+压力支持通气(SIMV+PSV)模式;研究组采用适应性支持通气(ASV)模式。观察2组的呼吸力学、呼吸形式、相关血流动力学指标、炎性因子情况。结果研究组VT明显高于对照组,指令呼吸频率、通气时间明显低于对照组(P<0.05)。研究组Ppeak、Pmean、Pplat等指标均明显低于对照组(P<0.05)。研究组CRP、PCT、AAG等指标水平均明显低于对照组,差异均具有统计学意义(P<0.05)。结论 ASV模式在合并Ⅱ型呼吸衰竭的COPD患者中的应用价值明显优于SIMV+PSV模式,值得推广。
Objective To observe the effect of different ventilation modes on COPD patients with type Ⅱ respiratory failure. Methods Eighty COPD patients with type Ⅱ respiratory failure were randomly divided into study group (40 cases) and control group (40 cases). The control group received SIMV + PSV mode. The study group adopted Adaptive Support Ventilation (ASV) mode. Respiratory mechanics, respiration patterns, relevant hemodynamics and inflammatory factors were observed in 2 groups. Results The VT of the study group was significantly higher than that of the control group, and the respiratory rate and ventilation time of the instruction were significantly lower than those of the control group (P <0.05). Ppeak, Pmean, Pplat and other indicators of the study group were significantly lower than the control group (P <0.05). The study group CRP, PCT, AAG and other indicators were significantly lower than the control group, the difference was statistically significant (P <0.05). Conclusion The ASV model is superior to SIMV + PSV model in COPD patients with type Ⅱ respiratory failure, which is worth promoting.