自从60年代初广泛应用麻疹疫苗以来,麻疹发病率显著降低,但要做到消除麻疹尚需努力完善免疫方案。Wild指出在部分发展中国家麻疹免疫尚未获得成功,不能终止季节性麻疹流行。半数儿童在出生后一年内已接触过麻疹病毒,故接种年龄应该提前。然而对4～6月龄儿童的免疫接种表明,其血清抗体阳转率仅64%,可 The incidence of measles has decreased significantly since the widespread use of measles vaccine in the early 1960s, but efforts are still needed to improve the immunization program to eliminate measles. Wild pointed out that measles immunity in some developing countries has not been successful and can not stop the seasonal measles epidemic. Half of children have been exposed to measles virus within one year of birth, so the vaccination age should be advanced. However, immunization of children aged 4 to 6 months showed that the positive rate of serum antibody was only 64%