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目的:观察补脾胃泻阴火升阳汤配合热敏灸法治疗溃疡性结肠炎的临床疗效.方法:选择符合纳入标准的溃疡性结肠炎住院患者100例,采用简单数字的随机方法分为治疗组和对照组,每组50例.对照组给予美沙拉嗪肠溶片1g,口服3/日治疗,治疗组在口服美沙拉嗪肠溶片的基础上采用补脾胃泻阴火升阳汤配合热敏灸法.观察2组患者治疗前后细胞因子水平、症状、大肠黏膜积分变化及临床疗效.结果:治疗后治疗组在细胞因子(Hs-CRP、IL-6、TNF-α)水平、症候积分(腹痛、腹泻、脓血便)、大肠黏膜方面比较有显著性差异(P＜0.05);治疗组临床疗效总有效率为92.00％,对照组临床疗效总有效率为82.00％,2者比较差异有统计学意义(P＜0.05).结论:补脾胃泻阴火升阳汤配合热敏灸法能够有效地缓解溃疡性结肠炎患者临床症状及大肠粘膜病变,改善细胞因子水平,值得进一步推广及应用.“,”Objective:To investigate the effect of Bupiwei Xieyinhuo Shengyang Decoction combined with thermal moxibustion for treating ulcerative colitis.Methods:100 hospitalized patients with ulcerative colitis were selected according to the inclusion criteria,and 50 cases were randomly divided into treatment group and controlled group.The controlled group was given oral treatment on Mesalazin Enteric-coated Tablets 1 g 3/d,the treatment group was given Bupiwei Xieyinhuo Shengyang Decoction combined with thermal moxibustion on the basis of Mesalazin Enteric-coated Tablets.Observation of 2 groups of patients before and after the treatment of cytokine levels,symptoms,and clinical efficacy of the integration of the colon mucosa.Results:The treatment group in the cytokine (Hs-CRP,IL-6,TNF-alpha) level,symptoms (abdominal pain,diarrhea,pus and blood stool),colorectal mucosa had significant difference between the treatment group (P ＜ 0.05);the total effective rate was 92％,the total effective rate of the controlled group was 82％,there was statistical a significant difference between the 2 groups (P ＜ 0.05).Conclusion:Bupiwei Xieyinhuo Shengyang Decoction combined with thermal moxibustion can effectively relieve the clinical symptoms of ulcerative colitis and colorectal mucosa in patients with lesions,improve the level of cytokines,it is worthy of further promotion and application.