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目的探讨肌钙蛋白T(c Tn T)在儿童病毒性脑炎中的检测价值。方法选取2012年1月—2013年1月保定市儿童医院儿科收治的符合《诸福棠实用儿科学》中关于病毒性脑炎诊断标准的患儿96例设为观察组,伴有意识障碍的患儿29例,无意识障碍的患儿19例;伴有惊厥者26例,无惊厥者22例。另选取同期住院的非脑部疾病患儿96例设为对照组。采用HITACHI公司生产的7170S全自动生化分析仪测定c Tn T及心肌酶水平。结果观察组患儿的c Tn T及心肌酶阳性率高于对照组(P<0.05)。观察组意识障碍患儿c Tn T及心肌酶阳性率高于无意识障碍患儿(P<0.05)。观察组惊厥患儿c Tn T及心肌酶阳性率与无惊厥患儿比较,差异有统计学意义(P<0.05)。结论儿童病毒性脑炎检测c Tn T有较高的检测价值、特异性,c Tn T灵敏度较心肌酶高,且阳性反应持续的时间较长。
Objective To investigate the diagnostic value of troponin T (c Tn T) in viral encephalitis in children. Methods From January 2012 to January 2013, Baoding Children’s Hospital pediatric treatment of children with compliance with the “Fu Beotang Practical Pediatrics” on the diagnostic criteria of viral encephalitis in 96 cases were treated as observation group, with disturbance of consciousness 29 cases of children, 19 children with unconsciousness; 26 cases with convulsions, 22 cases without convulsions. Another 96 cases of non-brain disease hospitalized in the same period as the control group. Using HITACHI company’s 7170S automatic biochemical analyzer cTn T and myocardial enzyme levels. Results The positive rates of cTn T and myocardial enzymes in the observation group were higher than those in the control group (P <0.05). The positive rates of cTn T and myocardial enzymes in children with disturbance of consciousness in observation group were higher than those in children without disturbance of consciousness (P <0.05). There was significant difference between cTn T and myocardial enzyme positive rate in children of observation group and those without convulsion (P <0.05). Conclusion The detection of cTn T in children with viral encephalitis has higher detection value. The specificity of cTn T is higher than that of myocardial enzymes, and the duration of positive reaction is longer.