新疆是食管癌高发区，尤以哈萨克族人群的患病率与死亡率明显高于其他民族。因此,我们对新疆几个主要民族食管癌组织的p53、p16、Rb蛋白的表达进行了比较研究。1材料与方法113例食管鳞癌标本系1993年～1998年新疆医科大学第一附属医院外科手术切除的存档蜡块。男性83例，女性30 Xinjiang is a high-incidence area for esophageal cancer. The prevalence and mortality of the Kazakh population are significantly higher than those of other ethnic groups. Therefore, we compared the expression of p53, p16, and Rb proteins in esophageal cancer tissues in several major ethnic groups in Xinjiang. 1Materials and methods 113 cases of esophageal squamous cell carcinoma specimens from 1993 to 1998 in the First Affiliated Hospital of Xinjiang Medical University surgical removal of the archived paraffin block. 83 males and 30 females