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角膜移植是许多脏器移植中历史最悠久的一种,移植片的愈合率也特别高。最近,作者统计的移植结果也表明,移植后五年内,约70%移植片保持透明。 (1)角膜移植不易引起排斥反应的理由有二:①角膜的解剖学特异性。角膜被其周围的巩膜,结膜及前房水等所包围,无血管组织。因此,所谓“免疫赦免区”(immunologically privileged site)的角膜,同机体免疫系统处于隔离状态,识别抗原比较困难,而且产生的免疫细胞也很难到达角膜。②与角膜的HLA分布有密
Corneal transplantation is the longest history of many organ transplant, the graft rate is also particularly high. Recently, the author’s statistical transplant results also showed that about 70% of the transplants remained transparent within five years after transplantation. (1) corneal transplantation is not easy to cause rejection for two reasons: ① corneal anatomical specificity. Cornea is surrounded by the sclera, conjunctiva and anterior chamber water surrounded by no vascular tissue. Therefore, the so-called “immunologically privileged site” of the cornea, which is isolated from the body’s immune system, recognizes the antigen more difficultly and the resulting immune cells hardly reach the cornea. ② and corneal HLA distribution is dense