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目的研究对比连续性肾脏替代治疗与间歇性血液透析治疗重症急性肾衰的临床效果。方法根据我院2015年8月~2016年8月期间接收86例重症急性肾衰竭患者入院时间的先后均分对照组和观察组。对照组患者采用间歇性血液透析治疗方法,观察组则采取连续肾脏替代治疗方法。对比分析两组患者取得的临床效果。结果观察组治疗有效率为95.3%,对照组治疗有效率为62.8%,差异显著(P<0.05);治疗前两组患者尿素氮、内生肌酐与血清肌酐水平并无明显差异(P>0.05),治疗后所有患者尿素氮、内生肌酐与血清肌酐水平均改善,且观察组优于对照组(P<0.05)。结论与间歇性血液透析治疗重症急性肾衰相对比,连续性肾脏替代治疗方法效果更为显著,可改善患者的临床指标,具有推广应用的价值。
Objective To compare the clinical effects of continuous renal replacement therapy and intermittent hemodialysis in the treatment of severe acute renal failure. Methods According to the hospital from August 2015 to August 2016 during the reception of 86 patients with severe acute renal failure admission time was divided into control group and observation group. Patients in the control group were treated with intermittent hemodialysis, while those in the observation group were treated with continuous renal replacement therapy. Comparative analysis of two groups of patients achieved clinical results. Results The effective rate of treatment was 95.3% in the observation group and 62.8% in the control group, with significant difference (P <0.05). There was no significant difference in the levels of urea nitrogen, creatinine and serum creatinine between the two groups before treatment (P> 0.05 ), After treatment all patients with urea nitrogen, creatinine and serum creatinine levels were improved, and the observation group was better than the control group (P <0.05). Conclusion Compared with intermittent hemodialysis in the treatment of severe acute renal failure, continuous renal replacement therapy is more effective and can improve the clinical indicators of patients with the value of popularization and application.