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目的探讨反流性食道炎(RE)与部分危险因素相关性。方法随机抽取本院消化科住院及门诊就诊患者353例,针对病例组患者予以胃镜检查,确保符合食道炎的诊疗标准。对于其余患者,则归入对照组。测定指标包含了空腹血糖,总胆固醇,甘油三酯,询问吸烟饮酒史。结果危险因素:吸烟(OR=1.838,P=0.035),年龄,血压及肥胖4类因素应当构成RE的关键性因素,吸烟,年龄,血压高,肥胖分别增加RE风险1.838,2.425,2.529,5.065倍。性别,族别,空腹血糖,总胆固醇,甘油三酯增加RE风险不明显。结论戒烟,降压,减肥可能在预防及治疗反流性食管炎方面起到一定作用。
Objective To investigate the relationship between reflux esophagitis (RE) and some risk factors. Methods A total of 353 inpatients and outpatients were randomly selected from our department of Gastroenterology. Gastroscopy was performed on patients in the case group to ensure compliance with the criteria for diagnosis and treatment of esophagitis. For the rest of the patients, the control group. Measurement indicators include fasting blood glucose, total cholesterol, triglycerides, asking smoking history. Results Risk factors: smoking (OR = 1.838, P = 0.035), age, blood pressure and obesity should constitute the key factors of RE. Smoking, age, high blood pressure and obesity increased the risk of RE respectively 1.838,2.425,2.529,5.065 Times Sex, ethnicity, fasting blood glucose, total cholesterol, triglycerides increased RE risk is not obvious. Conclusions Smoking cessation, blood pressure reduction and weight loss may play a role in the prevention and treatment of reflux esophagitis.