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本文采用DICKMAN缩合的方法,完成了N—噻唑基取代的甘氨酸乙酯,异喹啉酮盐酸盐及其β—酮酯的合成,并且进行了结构测试工作,以上化合物在文献中尚未见报导。
In this paper, the synthesis of N-thiazolyl substituted glycine ethyl ester, isoquinolinone hydrochloride and its β-ketoester was completed by DICKMAN condensation method, and the structural testing was performed. The above compounds have not been reported in the literature .