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目的了解输入性登革热传播的流行病学特征及病原学特点,进而提出针对性控制对策。方法建立了病例主动发现、报告的加强监测系统,根据病例的流行病学暴露史、临床表现和实验室检测结果进行诊断;采集患者血清标本进行血清学检测和病毒分离与序列测定。结果2004年7月22日~10月14日,浙江省慈溪市共报告了83例登革热病例,其中逍林镇82例,浒山街道1例。实验室诊断病例68例,临床诊断病例15例。男女性比为1∶1.9(29:54)。发病年龄为7~76岁,20~50岁组占78.31%(65/83),无明显职业特征;分离到登革热1型病毒,且与泰国的毒株有很高的同源性。结论病原学证实这是一起由登革1型病毒引起的输入性登革热爆发疫情,经采取综合性防制措施后,迅速控制了疫情。
Objective To understand the epidemiological and etiological characteristics of imported dengue fever and to propose targeted control strategies. Methods A surveillance system was established to detect and report the cases actively. According to the cases of epidemiological exposure, clinical manifestations and laboratory tests, serum samples were collected for serological detection and virus isolation and sequence determination. Results From July 22 to October 14, 2004, a total of 83 cases of dengue fever were reported in Cixi City, Zhejiang Province, including 82 cases of Xiao Lin and 1 case of Hu Shan Street. 68 cases of laboratory diagnosis, clinical diagnosis of 15 cases. The ratio of men to women is 1: 1.9 (29:54). The age of onset was from 7 to 76 years and 78.31% (65/83) from 20 to 50 years old. There was no obvious occupational characteristics. Dengue 1 virus was isolated and had high homology with that of Thailand. Conclusion The etiology confirmed that this was an outbreak of imported dengue fever caused by dengue type 1 virus. After comprehensive prevention and control measures were taken, the epidemic situation was quickly controlled.