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脑干肿瘤占儿童原发性颅内胶质瘤的10—15%,关于本病的自然病史及治疗已有报导,但对治疗后复发的类型未予研究,因此,照射范围未予肯定。本文报告了1967.1—1984.6 DuKe 大学医学中心收治的38例18岁以下脑干肿瘤患者,平均年龄8.9±3.9岁,男:女=1:1。全部病人经放射治疗,平均剂量52.6±5Gy,每次1.7—2.0Gy。23例局部照射,平均96cm~2,14例全脑照射后局部追加照射,平水278cm~2。25例可评价的复发病人中,22例(88%)在照射野内,2例在照射野内及照射野外,1例在全脑照射野内追加照射野外。全组5年存活率39%。结果表明:脑干肿瘤病人治疗
Brain stem tumors account for 10-15% of children with primary intracranial gliomas. The natural history and treatment of this disease have been reported, but the type of relapse after treatment has not been studied and therefore the extent of irradiation has not been affirmed. This article reports 38 patients with brain stem tumors under the age of 18 who were treated at the Duke University Medical Center from 1967 to January 1984 with an average age of 8.9 ± 3.9 years and a male to female ratio of 1: 1. All patients treated by radiation, the average dose of 52.6 ± 5Gy, each 1.7-2.0Gy. 23 cases of local irradiation, an average of 96cm ~ 2, 14 cases of local brain irradiation after additional irradiation, flat water 278cm ~ 2.25 evaluable recurrent patients, 22 cases (88%) in the field of irradiation, 2 cases in the field and In the field of irradiation, one patient was additionally irradiated in the wild in the whole brain irradiation field. The 5-year survival rate of 39%. The results show that: patients with brain stem cancer treatment