论文部分内容阅读
目的:探讨无充气颏下前庭联合入路腔镜甲状腺手术治疗甲状腺乳头状癌的可行性和安全性。方法:回顾性分析2020年11月至2021年4月在浙江大学医学院附属邵逸夫医院头颈外科接受无充气颏下前庭联合入路手术的41例甲状腺乳头状癌患者的临床和病理学资料。男性5例，女性36例；年龄（35.0±8.7）岁（范围：19~58岁）。甲状腺乳头状癌最大径为（7.6±5.8）mm（范围：2~30 mm）。颏下做1个长2.0 cm横切口为观察孔，置入1个10 mm套管和特制拉钩，口腔前庭内靠唇侧做2个长5 mm纵行切口为操作孔，各置入5 mm套管，操作方向为从头侧向尾侧。术后第1天和术后1个月检测下唇部及颏部感觉。记录手术时间、住院时间、清扫淋巴结数目及术后并发症。结果:所有病例均顺利在腔镜下完成手术，无中转开放手术。手术时间为（99±34）min（范围：50~180 min），术后住院时间为（3.4±2.2）d（范围：2~16 d）。清扫的中央区淋巴结数目为6（5）枚［n M（IQR）］（范围：1~25枚）。随访截至术后1个月，术后暂时性甲状旁腺功能减退2例，喉返神经损伤1例，继续随访评估是否为暂时性损伤。术后淋巴瘘、皮下积液及皮下局部红肿各1例，经过保守治疗均痊愈。下唇部轻微麻木1例，于术后1个月恢复正常。无永久性甲状旁腺功能减退发生，无术后出血发生，无颏部麻木发生。n 结论:无充气颏下前庭联合入路腔镜甲状腺手术治疗甲状腺乳头状癌是可行的，有临床应用价值。“,”Objective:To examine the safety and feasibility of gasless submental-transoral combined appoach endoscopic thyroidectomy for papillary thyroid carcinoma (PTC).Methods:A retrospective analysis of the clinical data of 41 patients with PTC who underwent the gasless submental-transoral combined appoach endoscopic thyroidectomy at the Department of Head and Neck Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine from November 2020 to April 2021. There were 5 males and 36 females with the age of (35.0±8.7) years (range: 19 to 58 years). A horizontal incision with a length of 2.0 cm is made under the chin as an observation hole, a 10 mm Trocar and a self-developed retractor are inserted, and two 5 mm longitudinal incisions are made on the labial side in the vestibule of the oral cavity as an operation hole, each inserting a 5 mm Trocar, the operation direction is from the cranial side to the caudal side. The sensation of the lower lip and chin was measured on the first day and one month postoperative. The operation time, hospital stay, the number of lymph nodes dissected and postoperative complications were recorded.Results:Surgical procedures in all cases were successfully completed under endoscopic approach without transfering to open surgery. The operation time was (99±34) minutes (range: 50 to 180 minutes) and the postoperative hospital stay was (3.4±2.2) days (range: 2 to 16 days). The maximum diameter of PTC was (7.6±5.8) mm (range: 2 to 30 mm), and the number of lymph nodes of the central compartment dissection was 6(5) (n M(IQR)) (range: 1 to 25). The duration of follow-up is 1 month after operation, and the follow-up method is adopted in outpatient clinic. Postoperation complications included 2 cases of transient hypoparathyroidism, One case of recurrent laryngeal nerve injury (continue to follow up to assess whether it is a temporary injury). Postoperative minor chyle leak, seroma, and local redness and swelling in 1 case each were cured after conservative treatment. 1 case of transient minor numbness of the lower lip was observed. No permanent hypoparathyroidism, postoperative bleeding and numbness of the chin was observed.n Conclusion:The gasless submental-transoral combined appoach endoscopic thyroidectomy is a feasible approach in selected PTC patients and has clinical application value.