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1 文献来源Hecht JR,Mitchell E,Chidiac T,et al.A randomized phase Ⅲ B trial of chemotherapy, Bevacizumab, and Panitumumab compared with chemotherapy and Bevacizumab alone for metastatic colorectal cancer [J]. J Clin Oncol, 2009, 27(5): 672-680.