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目的 :比较阿奇霉素与红霉素治疗小儿支原体肺炎的疗效。方法 :79例支原体病人分 2组 ,阿奇霉素组 41例 (男性 2 2例 ,女性 19例 ,年龄 7.9a±s 1.6a)用阿奇霉素 10mg/kg ,po ,qd× 3d。红霉素组 38例 (男性 2 1例 ,女性 17例 ,年龄 7.8a±2 .3a)用红霉素 2 5～ 30mg/ (kg·d) ,iv ,qd× 10d。结果 :有效率前者 98% ,后者 95 % (P >0 .0 5 ) ,显效率分别为 76%和 5 3% (P <0 .0 5 ) ,不良反应发生率分别为 7%和 39% (P <0 .0 1)。结论 :阿奇霉素治疗小儿支原体肺炎显效率优于红霉素 ,不良反应较红霉素小。
Objective: To compare the efficacy of azithromycin and erythromycin in the treatment of children with mycoplasma pneumonia. Methods: 79 cases of mycoplasma patients were divided into 2 groups, 41 cases of azithromycin group (22 males and 19 females, age 7.9a ± s 1.6a) with azithromycin 10mg / kg, po, qd × 3d. Erythromycin group 38 patients (21 males and 17 females, age 7.8a ± 2. 3a) with erythromycin 25 ~ 30mg / (kg · d), iv, qd × 10d. Results: The effective rate was 98% in the former group and 95% in the latter group (P> 0.05). The effective rates were 76% and 53% respectively (P <0.05), and the incidence rates of adverse reactions were 7% and 39% % (P <0 .0 1). Conclusion: Azithromycin is superior to erythromycin in the treatment of children with mycoplasma pneumonia and the adverse reaction is less than that of erythromycin.