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目的:探讨血清CA_(125)在卵巢子宫内膜异位囊肿诊断中的临床价值。方法:应用电化学发光法检测了46例卵巢子宫内膜异位囊肿组患者、16例卵巢瘤样病变组患者、38例卵巢良性肿瘤组患者及38例卵巢上皮性癌组患者的血清CA_(125)水平。结果:血清CA_(125)水平在卵巢子宫内膜异位囊肿组(84.05±70.51)U/ml及卵巢上皮性癌组(974.74+1479.66)U/ml显著升高,与卵巢瘤样病变组(22.59±22.61)U/ml、卵巢良性肿瘤组(24.73±19.95)U/ml比较,具有统计学意义(P<0.05);卵巢上皮性癌组(974.74±1479.66)U/ml的血清CA_(125)水平明显高于卵巢子宫内膜异位囊肿组(84.05±70.51)U/ml,具有统计学意义(P<0.05);卵巢瘤样病变组(22.59±22.61)U/ml与卵巢良性肿瘤组(24.73±19.95)U/ml比较,无统计学意义(P>0.05)。结论:卵巢子宫内膜异位囊肿患者血清CA_(125)水平增高,但低于卵巢上皮性癌,血清CA_(125)水平对于卵巢子宫内膜异位囊肿和卵巢上皮性癌的诊断有重要的临床价值。
Objective: To investigate the clinical value of serum CA 125 in the diagnosis of ovarian endometriosis. Methods: Electrochemiluminescence was used to detect the serum CA_ (4) in 46 cases of ovarian endometriosis group, 16 cases of ovarian neoplasia group, 38 cases of ovarian benign tumor group and 38 cases of ovarian epithelial carcinoma group 125) level. Results: Serum CA 125 levels were significantly higher in ovarian endometriotic cyst group (84.05 ± 70.51) U / ml and epithelial ovarian cancer group (974.74 ± 1479.66) U / ml than those in ovarian neoplasia group (22.59 ± 22.61) U / ml, ovarian benign tumor group (24.73 ± 19.95) U / ml, with statistical significance (P <0.05); The serum level of CA 125 in epithelial ovarian cancer group (974.74 ± 1479.66) ) Was significantly higher than that in ovarian endometriosis group (84.05 ± 70.51) U / ml, with statistical significance (P <0.05); ovarian tumor-like lesion group (22.59 ± 22.61) U / ml and ovarian benign tumor group (24.73 ± 19.95) U / ml, no statistical significance (P> 0.05). Conclusions: Serum CA 125 levels in patients with ovarian endometriosis are higher than those in patients with epithelial ovarian cancer, serum CA 125 levels are important for the diagnosis of ovarian endometriosis and ovarian epithelial carcinoma Clinical Value.