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目的 探讨成人Still 病(AOSD)的诊断及治疗。方法 分组分析30 例成人Still 病病例的临床特征及治疗。结果 临床特征:AOSD100% 发热,93-3% 关节肿痛,80% 皮疹,70% 咽痛。血类风湿因子(RF) 、抗链“O”(ASO)、血培养及咽培养均阴性,96-7 % 抗核抗体(ANA) 阴性,93-3 % 血沉(ESR) 增快,73-3% 白细胞( WBC) 增高。治疗:皮质激素有效率为100 % ,而非甾体抗炎药(NSAIDs)有效率5-5 % ,二者比较P< 0-01。结论 AOSD 以发热、皮疹、关节肿痛、咽痛,WBC增高、ESR 增快,RF、ASO、ANA 及血培养阴性为主要临床特点。诊断时应除外其它发热性疾病。治疗以应用皮质激素为首选
Objective To investigate the diagnosis and treatment of adult Still disease (AOSD). Methods The clinical characteristics and treatment of 30 cases of adult Still disease were analyzed by grouping. Results Clinical features: AOSD 100% fever, 93-3% joint swelling and pain, 80% rash, 70% sore throat. RF, anti-chain “O” (ASO), blood culture and pharyngeal culture were all negative, 96-7% ANA was negative, 93-3% erythrocyte sedimentation rate (ESR) 3% white blood cells (WBC) increased. Treatment: corticosteroid effective rate was 100%, while non-steroidal anti-inflammatory drugs (NSAIDs) effective rate of 5-5%, both P <0-01. Conclusion AOSD is the main clinical features of fever, rash, joint swelling and pain, sore throat, WBC increased, ESR increased, RF, ASO, ANA and blood culture negative. Diagnosis should be excluded except for other febrile diseases. Treatment of corticosteroids for the first choice