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慢性乙型肝炎的重要原因是乙肝病毒长期存在于体内,故治疗慢乙肝的根本疗法是进行有效的抗病毒治疗。我科于1990年开始,应用广东省药物研究所生产的单磷酸阿糖腺苷(Ara-AMP)治疗慢性乙型肝炎98人次,疗效较满意。现将资料完整的57例,报告如下: 临床资料选慢性乙型肝炎57例,平均年龄为28.63±11.58岁。用放射免疫法检测,57例HBs-Ag阳性,e抗原33例阳性。用生物素标记法检测H BV—DNA,26例阳性。谷丙转氨酶(ALT)高于1667nmolS~(-1)/L者27例,低于1667nmolS~(-1)/L者13例,正常者17例。
Chronic hepatitis B is an important reason for the long-existing hepatitis B virus in the body, so the treatment of chronic hepatitis B is the basic treatment for effective antiviral therapy. Our department began in 1990, the application of Guangdong Institute of Pharmaceutical production of monophosphate Ara-AMP (Ara-AMP) treatment of chronic hepatitis B 98 people, the effect is more satisfactory. The data now complete 57 cases, the report is as follows: Clinical data selected 57 cases of chronic hepatitis B, the average age was 28.63 ± 11.58 years. Radioimmunoassay, 57 cases of HBs-Ag-positive, e antigen 33 cases were positive. H BV-DNA was detected by biotin labeling, and 26 cases were positive. There were 27 cases with alanine aminotransferase (ALT) above 1667 nmol S -1 / L, 13 cases below 1667 nmol S -1 / L and 17 normal.