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双特异性单克隆抗体(BsAb)是在单克隆抗体(mAb)基础上研制成的一种新型抗体,其特点是一个BsAb分子可同时识别两种不同的抗原决定簇。采用BsAb再导向效应细胞治疗肿瘤,是近年来较有希望的一种特异性免疫疗法〔1〕。另外,也可用于免疫学检测和基础研究,实用性强。BsAb的
Bispecific monoclonal antibody (BsAb) is a new antibody developed on the basis of monoclonal antibody (mAb), which is characterized by a BsAb molecule that recognizes two different epitopes simultaneously. The use of BsAb redirecting effector cells to treat tumors is a more promising immunotherapy in recent years [1]. In addition, can also be used for immunological detection and basic research, practicality. BsAb’s