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目的：探讨酶联免疫吸附法（ELISA）检测丁型肝炎病毒抗体IgM（抗－HDIgM）与乙型肝炎病毒标志物（HBV—M）的相关性。方法：对182例执一HDIgM阳性标本进行HBV－M检测，并用变性正常人IgG中和部分乙型肝炎表面抗原（HBsAg）阳性标本和全部HBsAg阴性标本后再检测抗－HDIgM。结果。182例执－HDIgM阳性标本经中和试验排步RF干扰后，仅有122例阳性。HBsAg阳性标本在中和试验前后执－HDIgM阳性例数不变；HBsAg阴性标本则由中和试验前伪65例抗－HDIgM阳性文为多例，其余为阴性；并且。抗－HDIgM与HBV－M相关性“模式”也由12种变为7种，HBsAg阳性率和用性率在中和试验前后有显著性差异（P＜0．005）。结论：HBsAg阳性患者可根据执－HDIgM诊断混和感染HDV；HBsAg阴性患者必须进行其它试验如聚合酶链反应（PCR）检测HDV—RNA后才能诊断混和感染HDV，任性活动性ABV感染患者比急性HBV感染患者更容易混和感染HDV。
Objective: To investigate the correlation between hepatitis B virus antibody (IgM) and Hepatitis B virus (HBV-M) by enzyme-linked immunosorbent assay (ELISA). Methods: HBV-M was detected in 182 cases of HDIgM positive specimens. Anti-HDIgM was detected by neutralization of some HBsAg positive specimens and all negative HBsAg specimens with degenerated normal human IgG. result. Of the 182 patients with HDIgM-positive specimens, 122 were positive after RFIs were neutralized. HBsAg positive specimens in the neutralization test -HDIgM positive cases unchanged; HBsAg-negative samples from the neutralization test pseudo-anti-HDIgM pseudo-65 positive cases for the more cases, the rest is negative; The “pattern” of anti-HDIgM and HBV-M also changed from 12 to 7, and there was a significant difference (P <0.005) between HBsAg positive rate and sexual use rate before and after neutralization test. Conclusions: HBsAg-positive patients can be infected with HDV according to the diagnosis of executive-HDIgM. HBsAg-negative patients must undergo other tests such as polymerase chain reaction (PCR) to detect HDV-RNA before they can be diagnosed as HDV infection. Infected patients are more susceptible to HDV infection.