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目的:探讨视网膜光凝联合大活络胶囊治疗妊娠期糖尿病眼底病变的临床疗效。方法:选取妊娠期糖尿病眼底病变患者80例根据收治顺序分为观察组与对照组各40例,对照组患者给予激光光凝治疗,观察组患者在对照组的基础上加服大活络胶囊,对治疗后两组患者的视力改善、眼底荧光血管造影情况和眼底视网膜病变恢复情况等进行比较。结果:治疗3个月后观察组视力改善的显效率和总有效率分别为32.3%和80.0%,对照组分别为17.1%和67.1%,两组差异有统计学意义(P<0.05);眼底视网膜微动脉瘤数目和出血渗漏面积均显著小于对照组,眼底FFA改善的总有效率显著高于对照组,差异均有统计学意义(P<0.05);随访发现观察组中无复发病例,对照组中有1眼发生严重玻璃体出血。结论:视网膜光凝联合大活络胶囊治疗妊娠期糖尿病眼底病变疗效显著,视力改善明显,安全无复发,值得临床推广。
Objective: To investigate the clinical efficacy of retinal photocoagulation and DaoluoLuo capsule in the treatment of diabetic retinopathy. Methods: 80 cases of diabetic retinopathy in pregnancy were divided into observation group and control group according to the order of treatment, 40 cases in each group. The control group was treated with laser photocoagulation. The observation group was given Dafuluo capsule on the basis of control group Visual acuity, fundus fluorescein angiography and fundus retinal lesions recovery were compared between the two groups after treatment. Results: The effective rate and total effective rate of visual acuity in observation group after treatment for 3 months were 32.3% and 80.0% respectively, while the control group was 17.1% and 67.1% respectively. The difference between the two groups was statistically significant (P <0.05) The number of aneurysms in retina and the area of bleeding were significantly less than those in control group, and the total effective rate of fundus FFA improvement was significantly higher than that of control group (P <0.05). No recurrence was observed in the observation group, One of the patients in the control group developed severe vitreous hemorrhage. Conclusion: The combination of retinal photocoagulation and Dachengluo capsule in the treatment of diabetic retinopathy of pregnancy has significant curative effect, obvious visual acuity and no recurrence, which is worthy of clinical promotion.