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目的对本院质子泵抑制剂的使用情况进行分析,为临床合理、经济高效地使用药物提供参考依据。方法采用限定日剂量法,对本院2008～2010年质子泵抑制剂的用药频度(DDDs)、总消耗金额、日治疗费用等进行统计、分析。结果 2008年～2010年我院质子泵抑制剂的销售金额以每年大于53%的幅度递增。有六种药物的排序比接近1(0.5-1.5),同步性良好。泮托拉唑的DDDs稳居前1、2位,且泮托拉唑的(金额序号/DDDs序号)比为2.2,序号比最大,表明该药的使用频度较高,但其日治疗费用相对较低。结论质子泵抑制剂的使用数量和频率呈快速上升状态,表明近年来人们的胃部疾病不断增加,所耗费的治疗金额不断增加。
Objective To analyze the use of proton pump inhibitors in our hospital and provide reference for clinical use of drugs in a rational and cost-effective manner. Methods A limited daily dose method was used to calculate and analyze the DDDs, the total consumption and the daily treatment costs of proton pump inhibitors in our hospital from 2008 to 2010. Results From 2008 to 2010, the sales amount of proton pump inhibitors in our hospital increased by more than 53% annually. There are six drugs sort of close to 1 (0.5-1.5), synchronization is good. DDT of pantoprazole stayed in the first and second place, and the ratio of the amount of pantoprazole (the amount of serial number / DDDs) was 2.2, the serial number ratio was the largest, indicating that the drug was frequently used, but the daily treatment cost relatively low. Conclusions The number and frequency of use of proton pump inhibitors showed a rapid increase, indicating that in recent years, people’s stomach diseases have been increasing and the amount of treatment cost has been on the increase.