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目的:探讨尿毒清颗粒联合依那普利延缓慢性肾功能衰竭的临床价值。方法:将我院于2013年10月至2014年11月期间收治的88例CRF患者平均分为实验组和对照组,对照组患者给予依那普利、低蛋白饮食等药物进行常规治疗,实验组患者在此基础上给予尿毒清颗粒联合治疗,治疗2年后观察两组患者心率、血压等一般指标和BUN、Scr、24h尿蛋白量等重要指标,并观察记录并发症的发生情况。结果:实验组患者经过治疗BUN、Scr、24h尿蛋白量三个重要指标均有显著降低,且均明显低于对照组,而对照组患者BUN、Scr指标有明显降低,差异具有统计学意义(P<0.05);而实验组治疗后的有效率(95.5%)明显高于对照组(79.5%)。结论:尿毒清颗粒联合依那普利能够有效延缓CRF,且安全性较好。
Objective: To investigate the clinical value of Niaoduqing granule in combination with enalapril to delay chronic renal failure. Methods: A total of 88 CRF patients admitted to our hospital from October 2013 to November 2014 were divided into experimental group and control group. Patients in control group were given enalapril and low-protein diet for routine treatment. The experiment On the basis of this group, the patients were given combined treatment of Niaoduqing granule. After 2 years of treatment, the general indexes of heart rate and blood pressure and the indexes of BUN, Scr and urinary protein in 24 hours were observed. The occurrence of complication was recorded. Results: The three important indexes of BUN, Scr and 24h urinary protein in the experimental group were significantly lower than those in the control group, while the BUN and Scr indexes in the control group were significantly decreased (P <0.05), the difference was statistically significant P <0.05); while the experimental group after treatment efficiency (95.5%) was significantly higher than the control group (79.5%). Conclusion: Niaoduqing granule combined with enalapril can effectively delay CRF, and its safety is better.