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目的 :观察补阳还五汤对急性白血病的临床疗效。方法 :选取2013年1月至2015年12月期间,于新疆医科大学直属中医医院和新疆维吾尔自治区中医院门诊及住院并诊断为急性髓系细胞白血病的患者60例。将患者随机分为治疗组30例、对照组30例。治疗组采用补阳还五汤加减联合西医化疗治疗,对照组采用西医化疗治疗。治疗6周后观察两组临床治疗效果。结果 :治疗组有效率为86%对照组有效率为60%,差异有统计学意义(p<0.05)。治疗组出血、感染、骨髓抑制发生率均较对照组低,肝损害、肾损害、胃肠道症状发生率与对照组相比较均无统计学意义(p>0.05)。结论 :补阳还五汤加减联合西医治疗治疗急性白血病临床疗效优于西医治疗。
Objective: To observe the clinical effect of Buyang Huanwu Decoction on acute leukemia. Methods: From January 2013 to December 2015, 60 cases of patients with acute myeloid leukemia (AML) diagnosed as acute myeloid leukemia were enrolled and hospitalized in the directly affiliated TCM hospital of Xinjiang Medical University and the Xinjiang Uygur Autonomous Region Chinese Medicine Hospital. The patients were randomly divided into treatment group 30 cases, control group 30 cases. The treatment group was treated with Buyang Huanwu Decoction combined with western medicine and the control group with western medicine and chemotherapy. After 6 weeks of treatment, the clinical efficacy of the two groups was observed. Results: The effective rate was 86% in the treatment group and 60% in the control group, the difference was statistically significant (p <0.05). The incidence of hemorrhage, infection and myelosuppression in the treatment group were lower than those in the control group. There was no significant difference in the incidence of liver damage, renal damage and gastrointestinal symptoms between the treatment group and the control group (p> 0.05). Conclusion: The clinical curative effect of Buyang Huanwu Decoction combined with Western medicine in the treatment of acute leukemia is better than Western medicine.