【摘 要】
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目的:探讨MRI在儿童肝豆状核变性中的检查价值.材料和方法:对临床和生化证实30例肝豆状核变性的儿童进行治疗前后的脑部及腹部的MRI检查.结果:治疗前30例MRI中,19例(63.35%)
【机 构】
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200092上海第二医科大学附属新华医院放射科
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目的:探讨MRI在儿童肝豆状核变性中的检查价值.材料和方法:对临床和生化证实30例肝豆状核变性的儿童进行治疗前后的脑部及腹部的MRI检查.结果:治疗前30例MRI中,19例(63.35%)病人有脑部异常信号,异常信号分布:豆状核14例(73.7%),尾状核7例(36.8%),内囊6例(31.6%),丘脑4例(21.1%),脑干3例(15.8%).4例(21.1%)有轻度或中度脑萎缩.11例(36.6%)病人肝内大量弥漫性结节状异常信号.23例(76.7%)病人有不同程度的脾脏肿大.治疗后复查,19例脑部异常信号中,17例病变变小或消失,1例没有明显变化,1例加重.11例肝脏病变中,10例病变消失或变小,1例加重.23例脾脏肿大没有明显变化.结论:MRI对肝豆状核变性的诊断及预后具有重要意义.
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