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特异性体内试验例如皮试、鼻粘膜及支气管激发试验等的阳性反应有三种类型:(1)立即反应。(2)迟发反应(Latephase reaction,LPR)。(3)双相反应。立即反应的发生普遍认为与Ⅰ型变态反应有关,而LPR的发生机制观点不一,近年来关于LPR的研究有了很大进展,提出许多新的观点。LPR引起重视的主要原因是近年发现LPR比立即反应更加符合变态反应病人的特点,因此研究LPR对变态反应性疾病的防治可能有重要意义。一、发生机制 LPR发生机制的研究多年来已进行了大量的动物和临床试验。根据Pepys的早期观察认为LPR与Ⅲ型变态反应有关,他的
Specific in vivo tests such as skin tests, nasal mucosa and bronchial provocation test positive reaction there are three types: (1) immediate response. (2) Late reaction (LPR). (3) Biphasic reaction. The immediate reaction is generally believed to be related to the type Ⅰ allergic reaction, while the mechanism of LPR is different. In recent years, great progress has been made in the study of LPR, and many new ideas have been proposed. The main reason that LPR attracts attention is that LPR is more consistent with the characteristics of patients with allergic reactions than the immediate response in recent years, so the study of LPR on the prevention and treatment of allergic diseases may be of great significance. First, the mechanism of occurrence Mechanism of LPR over the years has conducted a large number of animal and clinical trials. According to the early observation of Pepys that LPR and type Ⅲ allergy related to his