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目的观察应用甲氨蝶呤及米非司酮保守治疗异位妊娠的疗效,为异位妊娠保守治疗提供参考。方法选择2013年至2014年吕梁市人民医院收治的异位妊娠保守治疗患者56例,根据药物治疗后是否成功分为成功组与失败组,比较两组的停经时间、腹痛天数及B超显示腹部包块大小、绒毛膜促性腺激素(HCG)水平,并用Logistic回归分析影响保守治疗成功的因素。结果两组停经时间比较差异有统计学意义(P<0.05),腹痛时间与阴道出血时间比较差异未见统计学意义(P>0.05)。血HCG水平、异位包块直径、停经天数是保守治疗失败的独立危险因素(P<0.05)。结论患者腹痛天数、包块大小及绒毛膜促性腺激素水平是影响保守治疗是否成功的关键因素,治疗时应根据以上几点确定是否采取保守治疗,以避免不必要的损失。
Objective To observe the curative effect of conservative treatment of ectopic pregnancy with methotrexate and mifepristine and to provide a reference for the conservative treatment of ectopic pregnancy. Methods 56 patients with conservative treatment of ectopic pregnancy admitted to Lvliang People’s Hospital from 2013 to 2014 were divided into two groups: successful group and failure group according to the success of drug treatment. The duration of menopause, abdominal pain days and B- Mass size, chorionic gonadotropin (HCG) level, and logistic regression analysis of the factors that influence the success of conservative treatment. Results There was significant difference in the menopause time between the two groups (P <0.05). There was no significant difference in the time between abdominal pain and vaginal bleeding (P> 0.05). Blood HCG levels, ectopic mass diameter, days of menopause were independent risk factors for conservative treatment failure (P <0.05). Conclusion The number of days of abdominal pain, the size of mass and the level of chorionic gonadotropin are the key factors that influence the success of conservative treatment. The treatment should be based on the above points to determine whether to take conservative treatment to avoid unnecessary losses.