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钒及其化合物的毒性研究已经很多,但是它对性腺、生殖机能和胚胎的影响还没有研究过。本文报道钒的性腺毒作用及其对生殖机能、胎儿、胚胎发育的影响。实验用110只性成熟雌雄大鼠,体重180～200 g,按研究工业毒物对生殖机能作用阈的方法进行,资料经统计学处理。按精子活力、渗透抵抗力,计算死、活和病理型精子数判断雄鼠性腺机能。睾丸形态学变化评价按以下指标:精子发生指数,正常精原细胞总数,有脱落生精上皮的曲细精管数和有12期有丝分裂的曲细精管数,以及睾丸大小和重量。为
There have been many studies on the toxicity of vanadium and its compounds, but its effects on gonads, reproductive functions and embryos have not been studied. This article reports the gonadal toxicity of vanadium and its effect on reproductive function, fetal and embryonic development. 110 male and female sexually mature rats weighing 180-200 g were used in the experiment. According to the method of studying the effect threshold of industrial toxicants on reproductive function, the data were statistically processed. According to sperm motility, osmotic resistance, calculate the number of dead, live and pathological sperm to determine the male gonadal function. Testicular morphological changes were assessed according to the following criteria: spermatogenic index, total number of normal spermatogonia, seminiferous tubules with exfoliated seminiferous epithelium and seminiferous tubules with 12 mitoses, and testicular size and weight. for