在近１１年中，我们应用国产骨水泥填充骨肿瘤术后骨缺据共２６例。初步观察，手术简便，比较安全，效果满意。重点随访了诊治的骨巨细胞瘤（Ⅰ～Ⅱ级）共１１例，平均４３．８月，仅１例复发，明显降低了复发率，关节功能较术前都有改进。１例术后发生病理骨折的骨巨细胞瘤再次手术时发现填入的骨水泥已发生松动。本文讨论了填入的骨水泥发生松动的原因，认为在骨水泥中加入脱钙骨基质或基质明胶，可避免松动发生。 In the past 11 years, we used bone cement to fill bone defects in 26 patients after operation. The initial observation was simple, safe, and satisfactory. A total of 11 cases of giant cell tumor of bone (grades I-II) were followed up with an average of 43.8 months. Only 1 patient relapsed, significantly reducing the recurrence rate, and the joint function was improved compared with preoperative. One case of bone giant cell tumor with pathological fracture after surgery was found to have loosened the bone cement filling. This article discusses the reason for the loosening of the implanted bone cement. It is considered that demineralized bone matrix or matrix gelatin can be added to the bone cement to avoid loosening.