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目的观察复方甘草酸苷联合软肝胶囊治疗慢性乙型肝炎肝纤维化的疗效。方法将120例慢性乙肝炎肝纤维化患者随机分为治疗组(复方甘草酸苷联合软肝胶囊)复方甘草酸苷组和软肝胶囊组治疗。结果治疗组治疗后临床疗效、肝功能的改善、肝纤维化指标的下降与治疗组及复方甘草酸苷组、软肝胶囊组比较差异有统计学意义(P<0.05)。结论复方甘草酸苷联合软肝胶囊在改善肝功能抗肝纤维化方面能明显提高临床疗效,稳定、持久、用药安全。
Objective To observe the curative effect of compound glycyrrhizin combined with RuanGan capsule on chronic hepatitis B liver fibrosis. Methods 120 patients with chronic hepatitis B liver fibrosis were randomly divided into treatment group (compound glycyrrhizin combined with RuanGan capsule) compound glycyrrhizin group and RuanGan capsule group. Results After treatment, the clinical curative effect, the improvement of liver function and the decrease of hepatic fibrosis index in the treatment group were statistically different from those in the treatment group and compound glycyrrhizin group and the soft liver capsule group (P <0.05). Conclusion Compound glycyrrhizin combined with RuanGan capsule can obviously improve the clinical curative effect, improve the liver function and prevent hepatic fibrosis. It is stable, durable and safe for medication.