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本文报道了转移因子对小鼠腹腔巨噬细胞吞噬功能的影响和对脾细胞E玫瑰花形成的作用。转移因子为本单位从健康猪脾细胞提取的针剂,含多核苷酸和多肽等低分子生物活性物质,每支含量为3×10~3个脾细胞提取物,每天一次0.5ml剂量注入小鼠体内,连续5次后取动物腹腔巨噬细胞和脾细胞悬液,测定其吞噬功能并观察E玫瑰花形成作用。结果表明,转移因子对小鼠腹腔巨噬细胞吞噬的百分率和吞噬指数与对照组比有明显差异(P<0.01),对小鼠脾细胞E玫瑰花形成作用与对照组比差异也极显著(P<0.01)。从而看出,转移因子能使小鼠腹腔巨噬细胞吞噬功能增强,亦能使特异的玫瑰花形成细胞中T淋巴细胞增多,增强了机体的免疫功能。
This article reported the effect of transfer factor on the phagocytosis of mouse peritoneal macrophages and the effect on the formation of splenocytes E rose. The transfer factor is an injection extracted from the spleen cells of healthy pigs and contains low molecular biological active substances such as polynucleotides and peptides. Each contains 3×10~3 spleen cell extracts and is injected into mice in 0.5 ml dose once a day. In vivo, animal peritoneal macrophages and splenocyte suspensions were taken 5 times in succession, and the phagocytic function was measured and the formation of E rose was observed. The results showed that the percentage of phagocytosis and phagocytosis index of peritoneal macrophages in mice was significantly different from that in the control group (P<0.01). The difference in the formation of E rose in mouse spleen cells was also significant compared with the control group (P<0.01). P<0.01). It can be seen that the transfer factor can enhance the phagocytosis of mouse peritoneal macrophages, and also increase the number of T lymphocytes in specific rose formation cells, and enhance the body’s immune function.