含百日咳无细胞菌苗组份的DTP(无细胞DTP)在2岁以上儿童中有80%的保护效果,但尚不清楚无细胞DTP对6月龄以下婴儿的免疫效果。为此作者对在1间住房的1次百日咳爆发进行了前瞻性研究。1名8月龄女婴住进一间住有约80名3岁以下的健康儿童的住所,该女婴住进后,发生了严重咳嗽,随后住进医院,血清学确诊为百日咳。 DTP (cell-free DTP) containing a B. pertussis cell-free vaccine component has an 80% protective effect in children over 2 years of age, but the immune effect of acellular DTP on infants under 6 months of age is unclear. To this end the authors conducted a prospective study of 1 pertussis eruption in a home. An 8-month-old baby girl admitted to a dwelling house with about 80 healthy children under the age of 3 years. After the baby entered the apartment, she developed a severe cough and then entered the hospital for serological diagnosis of whooping cough.