众所周知,恶性肿瘤时常伴有高钙血症;后者也可见于无骨转移的恶性肿瘤患者。因此,可能是肿瘤细胞产生的某种物质导致高钙血症而称之为肿瘤性高钙血症(HHM)。据报道,HHM 在恶性肿瘤中多见于肺鳞癌、肾癌、乳癌等。70年代已有许多HHM 的病例报告,其中大部分肿瘤可能产生异位甲状旁腺激素(PTH)。研究发现,尽管一部分病例血中PTH 浓度 As we all know, malignant tumors are often accompanied by hypercalcemia; the latter can also be seen in patients with malignant tumors without bone metastases. Therefore, it may be that a certain substance produced by tumor cells leads to hypercalcemia and is called neoplastic hypercalcemia (HHM). According to reports, HHM is more common in malignant tumors such as lung squamous cell carcinoma, kidney cancer, and breast cancer. There have been many HHM case reports in the 1970s, and most of these tumors may produce ectopic parathyroid hormone (PTH). Study found that although some patients have blood PTH concentrations