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目的:优选清肝利胆胶囊醇提工艺。方法:以大黄总蒽醌含量、乙醇浸出物量、三氯甲烷萃取物量和正丁醇萃取物量为综合指标,乙醇提取量、提取次数、提取时间为考察因素,通过正交试验优选清肝利胆胶囊最佳醇提工艺。结果:最佳醇提工艺为加8倍量80%乙醇提取2次,每次1.5h。结论:该提取工艺合理、简单可行,可为大生产提供理论依据。
Objective: To optimize Qing Gan Li Dan capsule alcohol extraction process. Methods: The total anthraquinone content of rhubarb, the amount of ethanol extract, the amount of chloroform extract and n-butanol extract as a comprehensive index, the amount of ethanol extraction, extraction times as the study factors, through orthogonal test Qinggan Lidan capsules The best alcohol extraction process. Results: The best alcohol extraction process for extraction plus eight times the amount of 80% ethanol extracted twice, each time 1.5h. Conclusion: The extraction process is reasonable, simple and feasible, can provide a theoretical basis for large-scale production.