论文部分内容阅读
目的探讨奥美拉唑治疗消化性溃疡急性大出血的临床疗效。方法入选的66例消化性溃疡急性大出血病例随机分为两组,奥美拉唑组36例在常规治疗基础上给予奥美拉唑40mg静脉滴注,每12h一次,连用5d,如无出血征象,继之以奥美拉唑20mg/d口服,转入抗消化性溃疡的常规治疗。西咪替丁组30例在常规治疗基础上给予西咪替丁400mg静脉滴注,每6h一次,连用5d,如出血停止,用西咪替丁200mg,饭前服,3次/d,400mg睡前服,转入抗消化性溃疡的常规治疗。结果奥美拉唑组与西咪替丁组的总有效率分别为94.44%和73.33%,经χ2检验,P<0.05,差异有统计学意义。结论奥美拉唑对消化性溃疡急性大出血有显著治疗作用。
Objective To investigate the clinical efficacy of omeprazole in the treatment of peptic ulcer acute hemorrhage. Methods Sixty-six cases of peptic ulcer acute hemorrhage were randomly divided into two groups. Omeprazole group (n = 36) was given 40 mg omeprazole intravenously once a day for 5 days on the basis of routine treatment. , Followed by omeprazole 20mg / d orally, into the conventional treatment of peptic ulcer. Cimetidine group 30 patients on the basis of conventional treatment given cimetidine 400mg intravenous infusion, once every 6h, once every 5d, such as bleeding stopped with cimetidine 200mg, pre-meal service, 3 times / d, 400mg Bedtime service, into the conventional treatment of peptic ulcer. Results The total effective rates of omeprazole group and cimetidine group were 94.44% and 73.33%, respectively. There was significant difference between the two groups (P <0.05). Conclusion Omeprazole has a significant therapeutic effect on acute hemorrhage of peptic ulcer.