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目的调查了解我国周围动脉闭塞性疾病(PAD)现患率及其相关影响因素。方法在我国7个大中城市15家三级甲等医院整群抽样入选50岁以上伴有一个以上危险因素的糖尿病患者以踝肱比(ABI)<0.9及脉波传导速度(PWV)>1400 cm/s 诊断 PAD,进行多因素回归分析其危险因素。结果调查的1397人中 PAD 的现患率为19.47%,其中男性占18.3%(122/664),女性占20.4%(150/733)。70岁以上 PAD 患病率上升到31.9%。PAD 与年龄、吸烟、收缩压、糖尿病病程及糖化血红蛋白均呈显著正相关。结论我国50岁以上糖尿病人群近五分之一患有 PAD。年龄、糖尿病病程、血糖水平和收缩期血压是 PAD 的危险因素。ABI、PWV 不仅是诊断 PAD 的手段,也可作为脑血管病(CVD)的预警指标。
Objective To investigate the prevalence of peripheral arterial occlusive disease (PAD) in China and its related factors. Methods A total of 15 tertiary hospitals in 7 large and medium-sized cities of China were enrolled in this study. Patients with diabetes over 50 years old with more than one risk factor were selected with ABI <0.9 and pulse wave velocity (PWV)> 1400 cm / s diagnosis of PAD, multivariate regression analysis of risk factors. Results The prevalence of PAD among 1397 people surveyed was 19.47%, of which 18.3% (122/664) were men and 20.4% (150/733) women. The prevalence of PAD over the age of 70 rose to 31.9%. PAD and age, smoking, systolic blood pressure, diabetes duration and glycosylated hemoglobin were positively correlated. Conclusion Nearly one-fifth of people with diabetes over the age of 50 have PAD. Age, duration of diabetes, blood glucose levels and systolic blood pressure are risk factors for PAD. ABI, PWV is not only a means of diagnosis of PAD, but also as an early warning indicator of cerebrovascular disease (CVD).