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目的探讨应激性高血糖对非糖尿病急性心肌梗死(AMI)预后的影响。方法选取2014年10月—2015年10月收治的AMI合并应激性高血糖的非糖尿病患者77例作为观察组,选取60例同期收治的急性心肌梗死未合并应激性高血糖患者作为对照组,记录二组患者入院后实验室检查CK-MB、ultra-nI、NT-proBNP结果,记录二组患者中心力衰竭、心律失常和死亡的发生率,并进行对比分析。结果观察组患者CK-MB、ultra-TnI和NT-proBNP水平均明显高于对照组,差异有统计学意义(P<0.05);观察组患者心力衰竭、心律失常、死亡的发生率均明显高于对照组,差异有统计学意义(P<0.05);心功能参数的比较观察组患者左心室射血分数(LVEF)显著低于对照组,而左心室舒张末期内径(LVDd)和左心室收缩期末期内径(LVDs)则显著高于对照组,差异均有统计学意义(P<0.05)。结论应激性高血糖导致非糖尿病AMI患者心肌功能损伤加重,预后可能更差。
Objective To investigate the effect of stress hyperglycemia on the prognosis of non-diabetic acute myocardial infarction (AMI). Methods A total of 77 non-diabetic AMI patients with stress hyperglycemia who were treated in our hospital from October 2014 to October 2015 were selected as the observation group. Sixty patients with acute myocardial infarction without stress hyperglycemia were selected as the control group The results of laboratory examination of CK-MB, ultra-nI and NT-proBNP in two groups were recorded. The incidences of heart failure, arrhythmia and death in the two groups were recorded and compared. Results The levels of CK-MB, ultra-TnI and NT-proBNP in the observation group were significantly higher than those in the control group (P <0.05). The incidence of heart failure, arrhythmia and death in the observation group was significantly higher (P <0.05). Compared with the control group, the left ventricular ejection fraction (LVEF) in the observation group was significantly lower than that in the control group, while the left ventricular end diastolic diameter (LVDd) and left ventricular contraction The LVDs were significantly higher than those in the control group (P <0.05). Conclusion Stress hyperglycemia may lead to worsening of cardiac function in patients with non-diabetic AMI and the prognosis may be worse.