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[目的]观察清热解毒口服液联合口腔炎喷雾剂治疗小儿手足口病疗效。[方法]使用随机平行对照方法,将60例门诊患儿按就诊顺序编号法随机分为两组。对照组30例利巴韦林颗粒,15～20mg/(kg.d),口服,3次/d,西瓜霜口腔喷雾,3次/d。治疗组清热解毒口服液,1～3岁5mL,≥3岁10mL口服,3次/d,口腔黏膜予口腔炎喷雾剂。观测临床症状、不良反应。连续治疗1疗程(5d),判定疗效。[结果]治疗组显效18例,有效10例,无效2例,总有效率93.30%。对照组显效6例,有效15例,无效9例,总有效率70.00%。治疗组总有效率高于对照组(P<0.05)。[结论]清热解毒口服液联合口腔炎喷雾剂治疗小儿手足口病,副反应小,疗效好,值得推广。
[Objective] To observe the curative effect of Qingrejiedu oral liquid combined with stomatitis spray on children hand-foot-mouth disease. [Methods] Using randomized parallel control method, 60 cases of outpatients were randomly divided into two groups according to the sequence number method. Control group, 30 cases of ribavirin particles, 15 ~ 20mg / (kg.d), orally, 3 times / d, watermelon cream oral spray, 3 times / d. Treatment group Qingrejiedu oral solution, 1 to 3 years old 5mL, ≥ 3 years old 10mL oral, 3 times / d, oral mucosa for stomatitis spray. Observed clinical symptoms, adverse reactions. Continuous treatment of a course of treatment (5d), to determine the efficacy. [Results] The treatment group markedly effective in 18 cases, effective in 10 cases, 2 cases, the total effective rate 93.30%. In the control group, 6 cases were markedly effective, 15 cases were effective, 9 cases were ineffective, and the total effective rate was 70.00%. The total effective rate in the treatment group was higher than that in the control group (P <0.05). [Conclusion] Qingrejiedu oral liquid combined with stomatitis spray for the treatment of hand-foot-mouth disease in children, with fewer side effects and good curative effect, which is worth to be popularized.