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(接7月上)女性更年期糖尿病的药物治疗主要口服降糖药物根据作用机制不同,分为促胰岛素分泌剂(磺脲类、格列奈类)、双胍类、噻唑烷二酮类胰岛素增敏剂、α-糖苷酶抑制剂、二基肽酶-VI(DPP-VI)抑制剂等。药物选择应基于2型糖尿病的两个主要病理生理改变——胰岛素抵抗和胰岛素分泌受损来考虑。此外,患者的血糖波动特点、年龄、体重、重要脏器功能等也是选择药物时要充分考虑的重要因素。联合用药时应采用具有机制互
(Followed by July) Drug treatment of menopause diabetes Main oral antidiabetic drugs according to different mechanism of action, divided into insulinotropic agents (sulfonylureas, glinides), biguanides, thiazolidinediones insulin sensitization Agents, alpha-glucosidase inhibitors, dipeptidyl-VI (DPP-VI) inhibitors and the like. Drug selection should be based on the two major pathophysiological changes in type 2 diabetes - insulin resistance and impaired insulin secretion. In addition, the characteristics of patients with blood glucose fluctuations, age, weight, vital organs function is also an important factor to be fully considered when choosing drugs. Combination therapy should be used to have a mechanism of mutual