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目的:研究关于多潘立酮联合阿米替林在治疗功能性消化不良的效果观察,以此来为在今后的工作中提供可靠的参考意见。方法:本文资料选自在我院2013年8月-2014年9月之间进行收治的120例患者资料,并随机分抽选为观察组和对照组,观察组患者60例,对照组患者60例,其中对照组患者资料给予多潘立酮进行治疗,观察组患者在此基础之上给予联合阿米替林进行治疗,两组患者均服药30d为一个疗程。结果:观察组60例资料给予的多潘立酮联合阿米替林治疗效果明显高于对照组给予的多潘立酮效果,观察组显示整体有效率为93.9%,占总体有效率52.6%,两组患者在接受治疗后均未出现严重不良反应。治疗3个疗程后,进行复检,观察组复发率占总体的10.3%,对照组复发率为30.2%。对照组两组效果对比比较是具有显著意义的(P<0.05)。结论:多潘立酮联合阿米替林治疗功能性消化不良无相关不良反应、治疗效果安全有效,大大减少复发率的产生,建议在临床上可以广泛的推广和运用。
Objective: To study the effect of domperidone combined with amitriptyline in the treatment of functional dyspepsia, in order to provide reliable reference for future work. Methods: The information in this article was selected from 120 patients admitted to our hospital from August 2013 to September 2014. The data were randomly divided into observation group and control group. 60 patients in the observation group and 60 patients in the control group For example, the data of the patients in the control group were given domperidone for treatment. The patients in the observation group were given the combination of amitriptyline on the basis of this treatment. Both groups took medication for 30 days as a course of treatment. Results: Domperidone combined with amitriptyline in the observation group was significantly higher than that of the domperidone treatment in the control group. The observation group showed that the overall effective rate was 93.9% and the total effective rate was 52.6%. The two groups of patients were treated No serious adverse reactions occurred afterwards. After 3 courses of treatment, retest, the observation group, the recurrence rate of 10.3% of the overall, the control group, the recurrence rate was 30.2%. The comparison of the two groups in the control group was significant (P <0.05). Conclusion: Domperidone combined with amitriptyline in the treatment of functional dyspepsia without adverse reactions, the treatment effect is safe and effective, greatly reducing the incidence of recurrence, it is recommended in the clinic can be widely promoted and applied.