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将86例变应性鼻炎患者(AR)分为三组,分别用H_1、H_2和H_1+H_2受体拮抗剂治疗,观察H_2受体拮抗剂的疗效。结果是H_2受体拮抗剂可使鼻细胞图中淋巴细胞增多并伴有临床症状改善,鼻分泌物中IgE含量降低,同时表明,H_1与H_2受体拮抗剂合用对治疗AR有协同作用。
Eighty-six patients with allergic rhinitis (AR) were divided into three groups and treated with H 1, H 2 and H 1 + H 2 receptor antagonists respectively to observe the effect of H 2 receptor antagonist. The result is that H 2 receptor antagonist can increase the number of lymphocytes in the nasal cell map with the improvement of clinical symptoms and reduce the IgE content in nasal secretions. It also shows that the combination of H 1 and H 2 receptor antagonists has a synergistic effect on the treatment of AR.