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将大肠杆菌内毒素粗制品经静脉注入不同动物,造成内毒素血症与休克模型,观察不同处理的疗效。主要指标包括存亡情况,动脉血压与血流速度(多普勒法)。从存活率来看,在小鼠空白38.5％(25/65只)、蟾酥61.5％(40/65只)、山莨菪碱64.7％(44/68只),在大鼠、山莨菪碱2/9只、蟾酥与山莨菪硷合用(以下简称为蟾山合液)4/10只;在家兔、山莨菪硷54.5％(12/22只),蟾酥66.7％(10/15只),蟾山合液84.0％
The crude product of E. coli endotoxin was intravenously injected into different animals to cause endotoxemia and shock model, and the efficacy of different treatments was observed. The main indicators include survival, arterial blood pressure and blood flow velocity (Doppler method). In terms of survival rate, 38.5% (25/65) mice, 61.5% (40/65) konjac, and 64.7% (44/68) anisodamine were found in rats, anisodamine 2/ Nine animals were used for the combination of 9 wolfberry and hawthorn (hereinafter referred to as Hayama mixture); 54.5% (12/22) were rabbits and hawthorns, and 66.7% (10/15) were clams. Mountain mixture 84.0%