将气味沙雷氏菌（Ｓｅｒｒａｔｉａ ｏｄｏｒｉｆｅｒａ）核糖体与该核糖体抗血清进行免疫印迹反应（Ｗｅｓｔｅｒｎ ｂｌｏｔ），发现分子质量为１６ ｋｕ 的蛋白质与抗血清有特异性免疫反应．用制备电泳从核糖体中分离得到１６ ｋｕ 组分，发现其特异性免疫活性依然存在，同时对荷Ｓ１８０ 实体瘤小鼠有明显的保护作用，对荷瘤小鼠的巨噬细胞和Ｔ 淋巴细胞增殖活性有激活作用，并能刺激体内ＮＫ 细胞，使之产生ＮＫ 活性，且作用时间较菌苗更持久．研究结果表明，１６ｋｕ 组分能通过刺激机体的免疫功能抑制肿瘤细胞的生长，是气味沙雷氏菌中抗肿瘤有效成分 Western blotting of Serratia odorifera ribosomes with this ribosomal antiserum showed that proteins with a molecular mass of 16 ku were specifically immunoreactive with antisera. The 16 ku fraction was isolated from the ribosome by preparative electrophoresis and found that its specific immunological activity still exists, at the same time on S180 solid tumor mice have obvious protective effect on tumor-bearing mouse macrophages and T lymphocytes Proliferative activity has an activating effect, and can stimulate the body’s NK cells, so that NK activity, and the role of time longer than the vaccine. The results show that 16ku components can inhibit the growth of tumor cells by stimulating the body’s immune function is the anti-tumor active ingredient of Serratia marcescens