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目的分析<46岁青年女性急性心肌梗死的临床及冠脉造影特点。方法 166例急性心肌梗死的女性患者,按年龄分为青年女性组50例(<46岁)和老年女性组116例(47~80岁)。比较两组的临床特征及冠脉造影特点。结果青年女性组中高血压、糖尿病、吸烟、低密度脂蛋白胆固醇(LDL-C)偏高比例高于老年女性组(P<0.05),两组A型血型家族史、冠心病家族史比较差异无统计学意义(P>0.05);冠脉造影结果青年女性组多累及左前降支,其次为右冠状动脉,老年女性组多累及右冠状动脉;青年女性组单支病变多见,老年女性组多支病变多见。结论高血压、糖尿病、高脂血症、吸烟等是青年女性急性心肌梗死的重要危险因素,单支病变为主;改变生活方式、缓解压力、控制LDL-C达标是预防青年女性急性心肌梗死的重要措施。
Objective To analyze the clinical features and coronary angiography of 46-year-old young women with acute myocardial infarction. Methods A total of 166 female patients with acute myocardial infarction were divided into two groups according to age, including 50 cases (<46 years) of young women and 116 cases (47-80 years) of elderly women. The clinical features and the characteristics of coronary angiography were compared between the two groups. Results The elevated proportion of hypertension, diabetes, smoking and low density lipoprotein cholesterol (LDL-C) in young women was higher than that in the elderly women (P <0.05). There was no significant difference in family history of type A blood group and family history of coronary heart disease between the two groups (P> 0.05). Coronary angiography showed that the young female group had more involvement of the left anterior descending branch, followed by the right coronary artery, the older female group had more involvement of the right coronary artery. The single-vessel disease of the young female group was more common and the older female group was more More common disease branch. Conclusions Hypertension, diabetes mellitus, hyperlipidemia and smoking are the important risk factors of acute myocardial infarction in young women, with single disease predominating. To change lifestyle, relieve stress and control LDL-C is to prevent acute myocardial infarction in young women Important measure