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本文搜集具有六指(趾)骨畸形的儿童6例,其中3例确诊为大骨节病。我们采用X线拍片、病理和超微结构的形态学手段,对其进行硒与大骨节病关系的探讨。结果表明硒对软骨坏死未显示出明显的修复作用,低硒不是大骨节病的唯一致病因素;硒可以改善软骨细胞膜性结构及增强膜性结构的功能;拇指外畸形的多指骨变化,不能代表其他手指骨的病变。
In this paper, six children with six-digit phalanges were collected, of which three were diagnosed as Kashin-Beck disease. We use X-ray film, pathology and ultrastructure of the morphological means of their selenium and KBD study. The results showed that selenium did not show obvious repair effect on cartilage necrosis. Low selenium was not the only causative factor of Kashin-Beck disease. Selenium could improve the membranous structure and enhance the membranous structure of chondrocytes. Multi-phalangeal changes of thumb external deformity could not Representative of other finger bone lesions.