铜(Copper,Cu)是生物体内代谢的必需微量元素之一,是细胞色素C氧化酶、超氧歧化酶、金属硫蛋白、多巴胺-b-单氧化酶、酪氨酸酶等辅酶中的重要金属离子。近年来的研究表明与铜转运相关连的蛋白是P型ATP酶,该酶缺陷可引起铜代谢异常,本文就体内铜代谢与其相关疾病的研究进展作一综述。 铜的正常代谢 一、来源与吸收 在一般饮食情况下,铜的摄入量婴幼 Copper (Cu) is one of the essential trace elements for metabolism in vivo and is important in coenzymes such as cytochrome C oxidase, superoxide dismutase, metallothionein, dopamine-b-monooxygenase and tyrosinase Metal ion. In recent years, studies have shown that the transporter associated with copper is a P-type ATPase, the enzyme can cause defects in copper metabolism abnormalities, in this paper, in vivo copper metabolism and its related diseases are reviewed. The normal metabolism of copper First, the source and absorption In the general diet, the intake of copper infants