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目的:观察中西医结合治疗与护理干预对慢性肾功能衰竭患者临床症状及生化指标的改善效果。方法:将60例慢性肾功能衰竭患者按照随机数字表法分组为对照组(西医治疗及常规护理)与观察组(在对照组治疗及护理的方案上加用肾衰宁颗粒治疗及中医辨证施护)各30例。比较2组患者临床症状(乏力、浮肿、食欲缺乏、恶心、呕吐)及治疗前、后生化指标(尿素氮(BUN)、血清肌酐(SCr)、肌酐清除率(CCr)、血红蛋白(Hb)、24 h尿蛋白变化;统计2组临床疗效及不良反应。结果:观察组患者临床症状缓解优于对照组,差异有统计学意义(P<0.05);2组患者BUN、SCr、CCr、Hb、24 h尿蛋白较治疗前改善,且观察组改善情况与对照组比较,差异均有统计学意义(P<0.05)。观察组临床总有效率83.3%高于对照组36.7%,差异有统计学意义(P<0.05);2组治疗期间无明显不良反应。结论:应用中西医治疗与护理可改善患者临床症状且安全。
Objective: To observe the improvement of clinical symptoms and biochemical indexes of patients with chronic renal failure treated by Integrative Medicine and Nursing Intervention. Methods: Sixty patients with chronic renal failure were divided into control group (Western medical treatment and routine nursing) and observation group according to the random number table (control group and treatment group were treated with Shenhuning granule and TCM syndrome differentiation Care) of the 30 cases. The clinical symptoms (fatigue, edema, loss of appetite, nausea and vomiting) and the biochemical parameters (BUN, SCr, CCr, Hb, 24 h urinary protein changes.Results: The relief of clinical symptoms in the observation group was better than that in the control group (P <0.05); The levels of BUN, SCr, CCr, Hb, 24 h urinary protein than before treatment to improve, and the observation group improved compared with the control group, the difference was statistically significant (P <0.05) .The total clinical effective rate was 83.3% in the observation group 36.7% of the control group, the difference was statistically significant (P0.05) .There was no significant adverse reaction in the two groups during the treatment.Conclusion: The treatment of traditional Chinese medicine and Western medicine can improve the clinical symptoms and safety of the patients.